The following information is extracted from the publication, 'All About Prostate Cancer' by Professor Fred Stephens, 2000, Oxford University Press, ISBN: 0 19 551404 1

In the early post-operative stages analgesics such as paracetamol may be required from time to time to relieve pain, but aspirin is not recommended as it may cause bleeding. Later aspirin can be a very useful drug in men of this age group. Not only does it relieve pain, but it also reduces risk of clotting in the legs and elsewhere; it also reduces risk of coronary artery disease and stroke. It may also reduce risk of some other health problems, for example bowel cancer.

For more severe pain, as for example from bone secondaries, the best treatment is to treat the secondaries in the bone. This is usually by radiotherapy if only one or two bones are affected, or by hormone treatment if the bone pain is widespread with several secondaries. Bone fractures will require orthopaedic treatment, possibly by surgical plating or pinning.

Result with the use of bisphosphonates or strontium 89 in relieving pain from bone secondaries have been so encouraging that these agents are now more or less standard treatment for bone pain in modern oncology units. (Discussed further in chapter 15 of the publication.)

If bone pain is severe and cannot otherwise be controlled, it might be necessary to use stronger pain-relieving drugs like morphine of pethidine.

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